Melanin-targeting radiotracers and their preclinical, translational, and clinical status: from past to future
X Zhang, Z Lin, Y Feng, F Kang, J Wang… - Journal of Nuclear …, 2024 - Soc Nuclear Med
… )-2-iodobenzamide in the diagnostic of primary and metastatic ocular melanoma [in French].
… melanoma and metastases with iodine-123-N-(2-diethylaminoethyl 4iodobenzamide). J …
… melanoma and metastases with iodine-123-N-(2-diethylaminoethyl 4iodobenzamide). J …
[HTML][HTML] Benzamide derivative radiotracers targeting melanin for melanoma imaging and therapy: Preclinical/clinical development and combination with other …
J Rouanet, M Quintana, P Auzeloux, F Cachin… - Pharmacology & …, 2021 - Elsevier
… richly pigmented tissues, leading to the first radiotracer N-(2-diethylaminoethyl)-4-iodobenzamide
(BZA), specifically designed to diagnose malignant melanoma (Michelot et al., 1991). …
(BZA), specifically designed to diagnose malignant melanoma (Michelot et al., 1991). …
N-(2-(dimethylamino) ethyl)-4-18F-fluorobenzamide: A novel molecular probe for high-contrast PET imaging of malignant melanoma
A Pyo, HS Kim, HS Kim, M Yun, DY Kim… - Journal of Nuclear …, 2019 - Soc Nuclear Med
… melanoma detection using SPECT (16–19). These probes were evaluated in B16 murine
melanoma… -DMFB to visualize LNs harboring metastatic malignant melanoma in mouse models…
melanoma… -DMFB to visualize LNs harboring metastatic malignant melanoma in mouse models…
[HTML][HTML] Evaluation of radioiodinated fluoronicotinamide/fluoropicolinamide-benzamide derivatives as theranostic agents for melanoma
CC Chen, YY Chen, YH Lo, MH Lin, CH Chang… - International Journal of …, 2020 - mdpi.com
… Malignant melanoma is the most harmful type of skin cancer and its incidence has increased
in this past … the potential of using 131 I-IFNABZA as a theranostic agent against melanoma. …
in this past … the potential of using 131 I-IFNABZA as a theranostic agent against melanoma. …
[HTML][HTML] Translating molecules into imaging—the development of new PET tracers for patients with melanoma
… a murine model of melanoma after administration of N-(2-diethylaminoethyl)-4-iodobenzamide
( 125 I… metastasis in 87 patients with a history of cutaneous or ocular melanoma. While the …
( 125 I… metastasis in 87 patients with a history of cutaneous or ocular melanoma. While the …
[HTML][HTML] Development of Radiofluorinated Nicotinamide/Picolinamide Derivatives as Diagnostic Probes for the Detection of Melanoma
YH Lo, TY Chang, CL Chen, MH Lin, HE Wang… - International Journal of …, 2021 - mdpi.com
… B16 melanoma (6.75 %ID/g) and liver (6.04 %ID/g) at 1 h after intravenous injection [6]. The
first clinical trial of 123 IN-(2-diethylaminoethyl)4-Iodobenzamide ( … to ocular melanoma, eye …
first clinical trial of 123 IN-(2-diethylaminoethyl)4-Iodobenzamide ( … to ocular melanoma, eye …
[HTML][HTML] Phase I study of [131I] ICF01012, a targeted radionuclide therapy, in metastatic melanoma: MELRIV-1 protocol
… approach for SPECT imaging of metastatic melanoma leading … Patients with cutaneous
melanomas will be recruited at the … -Ferrand and patients with uveal melanomas will be recruited …
melanomas will be recruited at the … -Ferrand and patients with uveal melanomas will be recruited …
Imaging Sigma-1 Receptor (S1R) Expression Using Iodine-124-Labeled 1-(4-Iodophenyl)-3-(2-adamantyl)guanidine ([124I]IPAG)
KK Gangangari, A Váradi, S Majumdar… - Molecular imaging and …, 2020 - Springer
… The tumor to background increases with time, and tumors could be clearly visualized starting
from 24 h post administration. Similar results were obtained in mice bearing LNCaP tumors. …
from 24 h post administration. Similar results were obtained in mice bearing LNCaP tumors. …
MC1R and melanin-based molecular probes for theranostic of melanoma and beyond
… in two melanoma patients for visualization of metastases … have been developed for melanoma
SPECT and PET imaging. … The N-(2-diethylaminoethyl)-4-iodobenzamide (BZA) was first …
SPECT and PET imaging. … The N-(2-diethylaminoethyl)-4-iodobenzamide (BZA) was first …